Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2094168 | 0.96 | LMNA (1.00) | — | |
| SCHEMBL9459 | 0.96 | — | — | |
| SCHEMBL9518993 | 0.92 | — | — | |
| SCHEMBL3453066 | 0.92 | — | — | |
| SCHEMBL11207256 | 0.92 | — | — | |
| SCHEMBL10435620 | 0.92 | — | — | |
| SCHEMBL5105333 | 0.92 | — | — | |
| Ammonia Solution, Strong SCHEMBL15232243 | 0.92 | LMNA (0.92) | — | |
| Hydrogen Sulfide SCHEMBL3719386 | 0.92 | — | — | |
| SCHEMBL2354348 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717203-A | Preparation method of C5 Grignard reagent | 肇庆巨元生化有限公司 | 2021-11-30 | — | — | CN | claimed |
| CN-113717203-B | Preparation method of C5 Grignard reagent | 肇庆巨元生化有限公司 | 2024-01-19 | — | — | CN | disclosed |
| CN-113717203-A | Preparation method of C5 Grignard reagent | 肇庆巨元生化有限公司 | 2021-11-30 | — | — | CN | disclosed |
| US-9065900-B2 | Method and system to shield mobile phones and devices to minimize radiation exposure | GREEN SWAN, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| US-20110157859-A1 | METHOD AND SYSTEM TO SHIELD MOBILE PHONES AND DEVICES TO MINIMIZE RADIATION EXPOSURE | GREEN SWAN, INC. | 2011-06-30 | — | — | US | disclosed |
| US-7968734-B2 | Organocatalysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-06-28 | — | — | US | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
| US-20060270649-A1 | AZETIDINE DERIVATIVES, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2006-11-30 | — | — | US | disclosed |
| WO-2006007586-A1 | ORGANOCATALYSTS AND METHODS OF USE IN CHEMICAL SYNTHESIS | SCIENCE & TECHNOLOGY CORPORATION @ UNM (US) | 2006-01-19 | — | — | WO | disclosed |
| US-6858603-B2 | Acetindine derivatives, their preparation and medicaments containing them | AVENTIS PHARMA S.A. (FR) | 2005-02-22 | — | — | US | disclosed |
| US-20040235816-A1 | Azetidine derivatives, their preparation and medicaments containing them | AVENTIS PHARMA S.A. (FR) | 2004-11-25 | — | — | US | disclosed |
| US-20030162808-A1 | Acetindine derivatives, their preparation and medicaments containing them | AVENTIS PHARMA S.A. (FR) | 2003-08-28 | — | — | US | disclosed |
| US-6518264-B2 | For treatment/prevention of psychoses, other brain disorders, and cardiovascular disorders | AVENTIS PHARMA S.A. (FR) | 2003-02-11 | — | — | US | disclosed |
| US-20020035102-A1 | Azetidine derivatives, their preparation and medicaments containing them | AVENTIS PHARMA S.A. (FR) | 2002-03-21 | — | — | US | disclosed |
| US-4464304-A | Vinyl Cyclopropyl compounds as precursors to fatty acid oxidation products | DUKE UNIVERSITY (US) | 1984-08-07 | — | — | US | disclosed |
| US-4350834-A | Vinyl cyclopropyl compounds as precursors to fatty acid oxidation products | DUKE UNIVERSITY (US) | 1982-09-21 | — | — | US | disclosed |
| US-4267339-A | ANTIDIABETIC AGENTS | PLANTEX LTD. (IL) | 1981-05-12 | — | — | US | disclosed |
| US-4137320-A | Pharmaceutical compositions containing imidazo(2,1-b)thiazoles and process for reducing blood sugar levels therewith | PLANTEX, LTD. (IL) | 1979-01-30 | — | — | US | disclosed |