Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21276172 | 1.00 | CARM1 (0.47) | CARM1PRMT6TP53NR1H2SMN1; SMN2 | |
| SCHEMBL22435955 | 0.87 | JAK1 (0.54) | NR1H2STSJAK2JAK1USP30 | |
| SCHEMBL10449417 | 0.87 | JAK1 (0.54) | NR1H2STSJAK2JAK1USP30 | |
| SCHEMBL10320157 | 0.87 | JAK1 (0.54) | NR1H2STSJAK2JAK1USP30 | |
| SCHEMBL4875893 | 0.87 | JAK1 (0.54) | NR1H2STSJAK2JAK1USP30 | |
| SCHEMBL4139961 | 0.85 | STS (0.56) | CARM1PRMT6TP53SMN1; SMN2STS | |
| SCHEMBL6269523 | 0.82 | JAK2 (0.50) | NR1H2STSJAK2JAK1USP30 | |
| SCHEMBL21276388 | 0.81 | NR1H2 (0.50) | TP53NR1H2SMN1; SMN2JAK2JAK1 | |
| SCHEMBL20557045 | 0.81 | NR1H2 (0.47) | TP53NR1H2STSJAK2JAK1 | |
| SCHEMBL21094341 | 0.81 | NR1H2 (0.47) | TP53NR1H2STSJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |