Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649560 | 0.82 | KDM1A (0.55) | KDM1AMAOBALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2649557 | 0.82 | KDM1A (0.55) | KDM1AMAOBALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL1412244 | 0.80 | ALDH1A1 (0.66) | KDM1AMAOBALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL4266535 | 0.80 | KMT2A (0.58) | KDM1AMAOBALDH1A1KMT2AMEN1 | |
| SCHEMBL5694937 | 0.80 | KMT2A (0.58) | KDM1AMAOBALDH1A1KMT2AMEN1 | |
| SCHEMBL4266530 | 0.80 | KMT2A (0.58) | KDM1AMAOBALDH1A1KMT2AMEN1 | |
| SCHEMBL6122749 | 0.79 | EPHX1 (0.47) | KDM1AMAOBKMT2AL3MBTL1DRD2 | |
| SCHEMBL6122752 | 0.79 | EPHX1 (0.47) | KDM1AMAOBKMT2AL3MBTL1DRD2 | |
| SCHEMBL14647010 | 0.78 | KDM1A (0.62) | KDM1AMAOBALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL2647959 | 0.78 | KDM1A (0.62) | KDM1AMAOBALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |