Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 20/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8214885 | 0.96 | HTR3A (0.74) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL3986685 | 0.89 | HTR3A (1.00) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL1004948 | 0.89 | HTR3A (1.00) | HTR3AKCNH2CYP2C19 | |
| Hydrochloric Acid SCHEMBL1007726 | 0.88 | HTR3A (0.98) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL8224160 | 0.84 | HTR3A (0.71) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL8215391 | 0.82 | HTR3A (0.55) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL1005577 | 0.82 | HTR3A (1.00) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL1006203 | 0.82 | HTR3A (1.00) | HTR3AKCNH2CYP2C19 | |
| Hydrochloric Acid SCHEMBL1005983 | 0.81 | HTR3A (0.98) | HTR3AKCNH2CYP2C19 | |
| SCHEMBL1007048 | 0.81 | HTR3A (0.67) | HTR3AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008019372-A2 | 2-AMINOBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS | ALBANY MOLECULAR RESEARCH, INC. (US) | 2008-02-14 | — | — | WO | disclosed |