Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 4/20 | 0.38 |
| ▸ | NPPA | P01160 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225196 | 0.88 | CA12 (0.44) | KCNN4HPGDNPSR1KDM4EALDH1A1 | |
| SCHEMBL7168982 | 0.83 | MME (0.45) | KCNN4NPSR1LMNAKIF11POLB | |
| SCHEMBL29908038 | 0.81 | NPSR1 (0.43) | KCNN4NPSR1ALDH1A1SMN1; SMN2KIF11 | |
| SCHEMBL3607588 | 0.80 | MME (0.47) | KCNN4NPSR1ALDH1A1SMN1; SMN2KIF11 | |
| SCHEMBL4627986 | 0.80 | NAALAD2 (0.51) | NPSR1ALDH1A1 | |
| SCHEMBL4627982 | 0.80 | NAALAD2 (0.51) | NPSR1ALDH1A1 | |
| SCHEMBL29478394 | 0.80 | NPSR1 (0.42) | KCNN4NPSR1KIF11MME | |
| SCHEMBL28500174 | 0.80 | NPSR1 (0.42) | KCNN4NPSR1KIF11MME | |
| SCHEMBL13726857 | 0.80 | NAALAD2 (0.51) | NPSR1ALDH1A1 | |
| SCHEMBL2742288 | 0.79 | KCNN4 (0.46) | KCNN4NPSR1ALDH1A1LMNAKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054865-A1 | FARNESYL TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041235-A1 | FARNESYL TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |