Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 9/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4460353 | 0.84 | MCL1 (0.47) | MCL1SCN4AXDHHDAC1HDAC2 | |
| SCHEMBL3270283 | 0.79 | NPY5R (0.38) | MCL1HDAC1HDAC2PPARDPPARA | |
| Trifluoroacetic Acid SCHEMBL4458367 | 0.79 | MCL1 (0.48) | MCL1SCN4AXDHHDAC1HDAC2 | |
| Trifluoroacetic Acid SCHEMBL8216241 | 0.79 | HDAC3 (0.40) | MCL1SCN9ASCN4AHDAC1HDAC2 | |
| SCHEMBL4686964 | 0.78 | MCL1 (0.46) | MCL1XDH | |
| SCHEMBL3269768 | 0.77 | MAPT (0.38) | HDAC1HDAC2 | |
| SCHEMBL4684167 | 0.76 | MCL1 (0.50) | MCL1BTK | |
| SCHEMBL3275341 | 0.76 | MCL1 (0.43) | MCL1SCN9ASCN4AXDH | |
| SCHEMBL8218222 | 0.76 | MCL1 (0.40) | MCL1SCN9ASCN4AXDHICMT | |
| SCHEMBL4460360 | 0.76 | LTA4H (0.47) | MCL1SCN4AXDHBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188133-B2 | Imidazole derivatives, preparation and user thereof as medicine | IPSEN PHARMA S.A.S. (FR) | 2012-05-29 | — | — | US | disclosed |