Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.67 |
| ▸ | MME | P08473 | 3/20 | 0.67 |
| ▸ | LTA4H | P09960 | 1/20 | 0.66 |
| ▸ | ACE | P12821 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216478 | 1.00 | ECE1 (0.67) | ECE1MMELTA4HACE | |
| SCHEMBL8216475 | 1.00 | ECE1 (0.67) | ECE1MMELTA4HACE | |
| SCHEMBL6170852 | 0.92 | ECE1 (0.73) | ECE1MMELTA4HACE | |
| SCHEMBL6171226 | 0.92 | ECE1 (0.73) | ECE1MMELTA4HACE | |
| SCHEMBL6171492 | 0.92 | ECE1 (0.73) | ECE1MMELTA4HACE | |
| SCHEMBL6169688 | 0.86 | ECE1 (0.77) | ECE1MMELTA4HACE | |
| SCHEMBL6169067 | 0.86 | ECE1 (0.77) | ECE1MMELTA4HACE | |
| SCHEMBL6169693 | 0.86 | ECE1 (0.77) | ECE1MMELTA4HACE | |
| SCHEMBL6169075 | 0.86 | ECE1 (0.77) | ECE1MMELTA4HACE | |
| SCHEMBL4193332 | 0.84 | MME (0.77) | ECE1MMELTA4HACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136842-A | INHIBITION OF ENDOTHELIN-CONVERTING ENZYME | HOECHST MARION ROUSSEL (FR) | 2000-10-24 | — | — | US | disclosed |