SCHEMBL8216547

SCHEMBL8216547

CC1CCC(C2CCC(C3CCC(CF)CC3)CC2)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4549772 1.00
SCHEMBL13746674 0.92
SCHEMBL13523750 0.92
SCHEMBL883345 0.92
SCHEMBL8220510 0.86
SCHEMBL12917717 0.82
SCHEMBL14001637 0.80
SCHEMBL8220123 0.79
SCHEMBL9926395 0.79
SCHEMBL18951183 0.78 ACHE (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2284148-B1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2016-03-02 EP disclosed
WO-2011137956-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2011-11-10 WO disclosed
WO-2010017868-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2010-02-18 WO disclosed
WO-2009129915-A1 THIOPHENE DERIVATIVES, AND LC MEDIA CONTAINING THE SAME MERCK PATENT GMBH (DE) 2009-10-29 WO disclosed
EP-1690916-B1 Mesogenic compounds, liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2008-03-12 EP disclosed
US-6030545-A HAVING A REDUCED VISCOSITY, A WIDE LIQUID CRYSTAL TEMPERATURE RANGE (HIGH CLEARING POINT), A HIGH CHEMICAL STABILITY (EXTREMELY HIGH SPECIFIC RESISTANCE, HIGH VOLTAGE HOLDING RATIO) AND A HIGH SOLUBILITY WITH OTHER LIQUID-CRYSTAL CHISSO CORPORATION (JP) 2000-02-29 US disclosed