Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084918 | 0.74 | IDH1 (0.37) | CYP11B2 | |
| SCHEMBL8097676 | 0.70 | GRM4 (0.36) | — | |
| SCHEMBL14264346 | 0.70 | CYP11B1 (0.34) | CYP11B2 | |
| SCHEMBL17729268 | 0.70 | GRM4 (0.36) | — | |
| SCHEMBL13983944 | 0.69 | NTRK1 (0.33) | — | |
| SCHEMBL9537354 | 0.69 | NTRK1 (0.33) | — | |
| SCHEMBL14425987 | 0.69 | NTRK1 (0.33) | — | |
| SCHEMBL1129532 | 0.67 | GRM4 (0.34) | — | |
| SCHEMBL12163198 | 0.65 | — | — | |
| SCHEMBL10297548 | 0.62 | NTRK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758883-B1 | Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors | SCHERING CORP (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2008021235-A2 | PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF 2-(QUINOLIN-5-YL)-4,5 DISUBSTITUTED-AZOLE DERIVATIVES | SCHERING CORPORATION (US) | 2008-02-21 | — | — | WO | disclosed |