Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216758 | 0.74 | CYP11B2 (0.30) | CYP11B2 | |
| SCHEMBL9535936 | 0.73 | IDH1 (0.33) | IDH1 | |
| SCHEMBL9537729 | 0.71 | SIGMAR1 (0.34) | IDH1 | |
| SCHEMBL8215076 | 0.70 | IDH1 (0.32) | IDH1 | |
| SCHEMBL9538574 | 0.69 | HRH3 (0.34) | IDH1 | |
| SCHEMBL13518217 | 0.67 | CYP19A1 (0.42) | IDH1 | |
| SCHEMBL7416538 | 0.66 | SIGMAR1 (0.31) | IDH1 | |
| SCHEMBL19561161 | 0.65 | IDH1 (0.36) | IDH1CYP11B2PTPN2PTPN1 | |
| SCHEMBL14431598 | 0.65 | CYP1A2 (0.33) | — | |
| SCHEMBL12162482 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009009003-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED 5-QUINOLYL-OXAZOLES AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | SCHERING CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |