SCHEMBL8217007

SCHEMBL8217007

O=C(O)CNC(=O)CCS.[Au]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.43
ALDH1A1 P00352 4/20 0.43
PTPN1 P18031 1/20 0.42
ACE P12821 1/20 0.41
MAPT P10636 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
POLB P06746 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
APEX1 P27695 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
GPR18 Q14330 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL459389 0.98 FAAH (0.44) FAAHALDH1A1PTPN1ACEMAPT
SCHEMBL468980 0.93 FAAH (0.42) FAAHALDH1A1PTPN1ACEMAPT
SCHEMBL22887712 0.93 FAAH (0.42) FAAHALDH1A1PTPN1ACEMAPT
SCHEMBL2804264 0.77 PTPN1 (0.55) FAAHALDH1A1PTPN1MAPTTDP1
SCHEMBL3253304 0.77 PHF8 (0.55) FAAHALDH1A1PTPN1MAPTTDP1
SCHEMBL2808310 0.77 PTPN1 (0.60) FAAHALDH1A1PTPN1MAPTTDP1
SCHEMBL75812 0.77
SCHEMBL18618642 0.77 FAAH (0.62) FAAHALDH1A1PTPN1MAPTTDP1
SCHEMBL16108691 0.76 ECE1 (0.56) FAAHACEMMEHDAC3HDAC4
SCHEMBL11306604 0.76 CA1 (0.38) ALDH1A1ACERECQLHDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6013798-A WATER-BASED COMPOSITION FOR DECORATING SUBSTRATE, I.E., CERAMIC OR GLASS WITH BRIGHT GOLD FILM UPON FIRING COMPRISING A NON-RADIOACTIVE GOLD THIOLATE JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2000-01-11 US claimed
US-6013798-A WATER-BASED COMPOSITION FOR DECORATING SUBSTRATE, I.E., CERAMIC OR GLASS WITH BRIGHT GOLD FILM UPON FIRING COMPRISING A NON-RADIOACTIVE GOLD THIOLATE JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2000-01-11 US disclosed
EP-0668264-B1 Sulfur containing organic gold compounds, process for their preparation and their use CERDEC AG (DE) 1999-09-22 EP disclosed
US-5744245-A POLYMERIC RESIN IN SOLUTION, WATER, COSOLVENT, AND THIOLATE OF PRECIOUS METAL JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1998-04-28 US disclosed
US-5721303-A PREPARATION FOR PRODUCING GOLD DECORATION COMPRISING SPECIFIED ORGANOSULFUR GOLD COMPOUND DISSOLVED IN AQUEOUS SOLVENT SYSTEM, POLYMERIC BINDER CERDEC AKTIENGESELLSCHAFT KERAMISCHE FARBEN (DE) 1998-02-24 US disclosed
US-5639901-A PRECIPITATE FORMED BY DISSOLVING GOLD(I) DIMERCAPTOCARBOXYLIC ACID IN AN AQUEOUS BASE AND ADDING MINERAL ACID TO LOWER PH TO 2 OR LESS; FIRED OVERGLAZE DECORATION FOR GLASS, CERAMICS CERDEC AKTIENGESELLSCHAFT KERAMISCHE FARBEN (DE) 1997-06-17 US disclosed
EP-0668264-A2 Sulfur containing organic gold compounds, process for their preparation and their use CERDEC AKTIENGESELLSCHAFT KERAMISCHE FARBEN (DE) 1995-08-23 EP disclosed
EP-0514073-B1 Precious metal composition JOHNSON MATTHEY PLC (GB) 1995-07-05 EP disclosed
US-5401535-A Precious metal composition JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1995-03-28 US disclosed
US-5281635-A Polym,er resin and water-solvent solution of thiolate of platinum, palladium, gold, or silver for forming film on firing JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1994-01-25 US disclosed
EP-0514073-A2 Precious metal composition JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1992-11-19 EP disclosed