Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217159 | 0.83 | SLC2A1 (0.48) | SLC2A1KCNH2MAT2A | |
| SCHEMBL8215088 | 0.82 | SLC2A1 (1.00) | SLC2A1KCNH2 | |
| SCHEMBL178862 | 0.77 | SLC2A1 (0.52) | SLC2A1KCNH2 | |
| SCHEMBL10069524 | 0.73 | SLC2A1 (0.48) | SLC2A1KCNH2 | |
| SCHEMBL8217165 | 0.73 | SLC2A1 (0.48) | SLC2A1KCNH2 | |
| SCHEMBL178856 | 0.70 | SLC2A1 (0.43) | SLC2A1 | |
| SCHEMBL10069521 | 0.65 | SLC2A1 (0.43) | SLC2A1 | |
| SCHEMBL8215084 | 0.65 | SLC2A1 (0.69) | SLC2A1KCNH2 | |
| SCHEMBL7209594 | 0.64 | SLC2A1 (0.62) | SLC2A1KCNH2 | |
| SCHEMBL178859 | 0.62 | MARS1 (0.51) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000071524-A1 | 2-NH-PYRIDONES AND PYRIMIDONES AS MRS INHIBITORS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-30 | — | — | WO | disclosed |
| US-6013619-A | APPLYING GAS POSITIVE END-EXPIRATORY PRESSURE WITH VENTILATOR INTO LUNG SECTION OF MAMMAL, INSTILLING LAVAGE COMPOSITION CONTAINING DILUTE SURFACTANT IN A PHARMACEUTICALLY ACCEPTABLE AQUEOUS MEDIUM INTO LUNG, REMOVING PULMONARY FLUID | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-01-11 | — | — | US | disclosed |