Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.71 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.71 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | SHBG | P04278 | 3/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.71 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | PGR | P06401 | 2/20 | 0.65 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342689 | 1.00 | HSD17B10 (0.71) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| SCHEMBL4971575 | 0.90 | HSD17B10 (0.71) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| SCHEMBL28023466 | 0.90 | HSD17B10 (0.71) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| SCHEMBL259724 | 0.90 | HSD17B10 (0.70) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| SCHEMBL5082089 | 0.90 | HSD17B10 (0.70) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| SCHEMBL28941264 | 0.89 | HSD17B10 (0.69) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| SCHEMBL27607895 | 0.89 | HSD17B10 (0.69) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| SCHEMBL30483614 | 0.88 | HSD17B10 (0.68) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| SCHEMBL21875771 | 0.86 | HSD17B10 (0.66) | HSD17B10NR3C1SERPINA6LMNATSHR | |
| SCHEMBL23645479 | 0.86 | HSD17B10 (0.69) | HSD17B10NR3C1SERPINA6LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283889-B1 | METHOD AND ASSAY FOR DIAGNOSING RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS IN A SUBJECT | EUROIMMUN MEDIZINISCHE LABORDIAGNOSTIKA AG (DE) | 2020-02-26 | — | — | EP | claimed |
| EP-1792582-B1 | INDWELLING STENT | KANEKA CORP (JP) | 2018-04-04 | — | — | EP | claimed |
| EP-0494224-B1 | USE OF STEROID HORMONES IN COMPOSITIONS FOR INDUCING T CELL LYMPHOKINE PRODUCTION | UNIV UTAH RES FOUND (US) | 2000-05-10 | — | — | EP | claimed |