Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 11/20 | 0.41 |
| ▸ | FNTB | P49356 | 11/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzonitrile SCHEMBL8216189 | 0.82 | FNTA (0.42) | TSHRFNTAFNTBPGGT1BCYP11B1 | |
| SCHEMBL378803 | 0.81 | — | — | |
| SCHEMBL6208653 | 0.75 | TDP1 (0.52) | FNTAFNTBPGGT1BTDP1HPGDS | |
| SCHEMBL945843 | 0.73 | — | — | |
| Benzonitrile SCHEMBL28620415 | 0.68 | TSHR (0.64) | TSHR | |
| Benzonitrile SCHEMBL1325381 | 0.66 | TSHR (0.88) | TSHR | |
| Benzonitrile SCHEMBL27895262 | 0.66 | TSHR (0.88) | TSHR | |
| Benzonitrile SCHEMBL1326469 | 0.66 | TSHR (0.88) | TSHR | |
| Benzonitrile SCHEMBL28346351 | 0.66 | TSHR (0.88) | TSHR | |
| Benzonitrile SCHEMBL2154015 | 0.66 | TSHR (0.88) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000034437-A2 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2000-06-15 | — | — | WO | disclosed |