Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL821750 | 1.00 | LMNA (0.35) | LMNAGAAS1PR1VCAM1ALDH1A1 | |
| SCHEMBL821351 | 0.94 | LMNA (0.36) | LMNAGAAVCAM1ALDH1A1MEN1 | |
| SCHEMBL821350 | 0.94 | LMNA (0.36) | LMNAGAAVCAM1ALDH1A1MEN1 | |
| SCHEMBL821963 | 0.92 | KDR (0.35) | LMNAS1PR1ALDH1A1KDRMEN1 | |
| SCHEMBL821964 | 0.92 | KDR (0.35) | LMNAS1PR1ALDH1A1KDRMEN1 | |
| SCHEMBL821648 | 0.90 | LMNA (0.37) | LMNAGAAVCAM1ALDH1A1MEN1 | |
| SCHEMBL821649 | 0.90 | LMNA (0.37) | LMNAGAAVCAM1ALDH1A1MEN1 | |
| SCHEMBL820799 | 0.89 | LMNA (0.42) | LMNAGAAVCAM1ALDH1A1KDR | |
| SCHEMBL820800 | 0.89 | LMNA (0.42) | LMNAGAAVCAM1ALDH1A1KDR | |
| SCHEMBL821309 | 0.87 | MEN1 (0.37) | LMNAGAAALDH1A1KDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399569-B1 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | HENKEL AG & CO KGAA (DE) | 2018-07-18 | — | — | EP | claimed |
| EP-2399569-A2 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | Henkel AG & Co. KGaA (DE) | 2011-12-28 | — | — | EP | claimed |
| EP-2399569-B1 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | HENKEL AG & CO KGAA (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2399569-A2 | Cationic azo dyes with a special grouping of the 4-Aza-1-azoniabicyclo[2.2.2]octane and means of colouring keratinic fibres | Henkel AG & Co. KGaA (DE) | 2011-12-28 | — | — | EP | disclosed |