Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8508413 | 1.00 | CTSK (0.50) | CTSKCTSSCAPN1PTPN1PTPRA | |
| SCHEMBL8511839 | 0.92 | CTSK (0.51) | CTSKCTSSCAPN1PTPN1PTPRA | |
| SCHEMBL23007632 | 0.89 | CTSK (0.53) | CTSKCTSSCAPN1PTPN1PTPRA | |
| SCHEMBL11113157 | 0.86 | CTSK (0.51) | CTSKCTSSCAPN1PTPN1PTPRA | |
| SCHEMBL13855558 | 0.84 | CTSK (0.49) | CTSKCTSSCAPN1PTPN1PTPRA | |
| SCHEMBL23007877 | 0.84 | CTSK (0.49) | CTSKCTSSCAPN1PTPN1PTPRA | |
| SCHEMBL506750 | 0.83 | CTSK (0.55) | CTSKCTSSCAPN1PTPN1PTPRA | |
| SCHEMBL20542797 | 0.83 | CTSK (0.70) | CTSKCTSSCAPN1PTPN1PTPRA | |
| SCHEMBL20542796 | 0.83 | CTSK (0.70) | CTSKCTSSCAPN1PTPN1PTPRA | |
| SCHEMBL21561570 | 0.83 | CTSK (0.55) | CTSKCTSSCAPN1PTPN1PTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037668-A1 | TRANSFECTION PARTICLES | Boehringer Ingelheim International GmbH (DE) | 2000-09-27 | — | — | EP | disclosed |
| EP-0945138-A1 | Transfection particles | Université Louis Pasteur de Strasbourg (FR) | 1999-09-29 | — | — | EP | disclosed |
| WO-1999029349-A1 | TRANSFECTION PARTICLES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 1999-06-17 | — | — | WO | disclosed |