Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 7/20 | 0.75 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8265831 | 0.88 | ADK (0.75) | ADKHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL14635803 | 0.85 | ADK (1.00) | ADKHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL8196407 | 0.84 | ADK (0.77) | ADKHPGDPTK2BCYP1A2CYP2C9 | |
| SCHEMBL2039002 | 0.81 | ADK (0.78) | ADKHPGDPTK2BCYP1A2CYP2C9 | |
| SCHEMBL8207317 | 0.81 | ADK (0.78) | ADKHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL8267958 | 0.80 | ADK (0.83) | ADKHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL2037666 | 0.79 | ADK (0.82) | ADKHPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL2036788 | 0.79 | ADK (0.68) | ADKHPGDPTK2BCYP1A2CYP2C9 | |
| SCHEMBL2039851 | 0.79 | HPGD (0.89) | ADKHPGDPTK2BCYP1A2CYP2C9 | |
| SCHEMBL2035229 | 0.78 | ADK (0.84) | ADKHPGDKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | claimed |