Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780388 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1MAPTGAA | |
| SCHEMBL29430899 | 0.83 | ALDH1A1 (0.50) | ALDH1A1KDM4EL3MBTL1MAPTGAA | |
| SCHEMBL29449219 | 0.68 | ALDH1A1 (0.46) | ALDH1A1KDM4EL3MBTL1MAPTGAA | |
| SCHEMBL40549 | 0.68 | ALDH1A1 (0.46) | ALDH1A1KDM4EL3MBTL1MAPTGAA | |
| Hydrochloric Acid SCHEMBL11772004 | 0.66 | ALDH1A1 (0.44) | ALDH1A1KDM4EL3MBTL1MAPTGAA | |
| SCHEMBL724771 | 0.66 | — | — | |
| SCHEMBL2964383 | 0.66 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1MAPTGAA | |
| SCHEMBL24439575 | 0.66 | MAPT (0.53) | ALDH1A1KDM4EL3MBTL1MAPTGAA | |
| SCHEMBL30768365 | 0.66 | TEAD1 (0.47) | ALDH1A1KDM4EL3MBTL1MAPTGAA | |
| SCHEMBL24750328 | 0.66 | TEAD1 (0.47) | ALDH1A1KDM4EL3MBTL1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019720-A1 | COMBINATORIAL PROCESS FOR PREPARING TETRAHYDROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998027427-A1 | COMBINATORIAL PROCESS FOR PREPARING TETRAHYDROQUINOLINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |