Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.40 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218194 | 0.84 | PDE5A (0.55) | PDE5ABCDIN3D | |
| SCHEMBL4725990 | 0.79 | MAPK1 (0.59) | PDE5AALDH1A1KDM4EHPGDHTT | |
| SCHEMBL4725339 | 0.79 | PDE11A (0.54) | PDE5APDE11A | |
| SCHEMBL4725293 | 0.78 | MAPK1 (0.52) | PDE5AALDH1A1PDE11AKDM4EHPGD | |
| SCHEMBL27845606 | 0.77 | PDE5A (0.56) | PDE5A | |
| SCHEMBL7502930 | 0.73 | PDE5A (0.64) | PDE5ABCDIN3D | |
| SCHEMBL4728689 | 0.73 | PDE5A (0.55) | PDE5AALDH1A1PDE11AKDM4EHPGD | |
| SCHEMBL4727580 | 0.73 | PDE5A (0.55) | PDE5AALDH1A1KDM4EHPGDHTT | |
| SCHEMBL5118817 | 0.73 | PDE5A (0.54) | PDE5ABCDIN3D | |
| SCHEMBL7498505 | 0.73 | PDE5A (0.55) | PDE5ABCDIN3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008020711-A1 | QUINAZOLINE DERIVATIVE AS PHOSPHODIESTERASE INHIBITOR AND A PROCESS FOR PREPARING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2008-02-21 | — | — | WO | disclosed |