SCHEMBL8218343

SCHEMBL8218343

C=C(CC)CCC1CCC(/C=C/C2CCC(CCC)CC2)CC1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8218348 1.00 LMNA (0.30) LMNAMAPK1HTT
SCHEMBL8209577 0.87 LMNA (0.34) LMNAMAPK1HTT
SCHEMBL8218322 0.84 TLR4 (0.36) LMNAMAPK1HTT
SCHEMBL8220795 0.84 HTT (0.40) LMNAMAPK1HTT
SCHEMBL28082355 0.81 CYP1A2 (0.37) LMNAMAPK1HTT
SCHEMBL7556338 0.81 CYP1A2 (0.37) LMNAMAPK1HTT
SCHEMBL7556346 0.81 CYP1A2 (0.37) LMNAMAPK1HTT
SCHEMBL28082543 0.81 CYP1A2 (0.37) LMNAMAPK1HTT
SCHEMBL7556331 0.81 CYP1A2 (0.37) LMNAMAPK1HTT
SCHEMBL28082356 0.81 CYP1A2 (0.37) LMNAMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143198-A SUITABLE FOR USE AS ELECTRO-OPTICAL DISPLAY MATERIALS; LIQUID CRYSTALLINE COMPOUND HAVING A LARGE ELASTIC CONSTANT RATIO, EXCELLENT COMPATIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUND, AND LOW TEMPERATURE CHEMICAL STABILITY CHISSO CORPORATION (JP) 2000-11-07 US disclosed
EP-0828700-A1 LIQUID CRYSTALLINE COMPOUNDS HAVING EXO-METHYLENE SITE AND LIQUID CRYSTAL COMPOSITIONS COMPRISING THE SAME CHISSO CORPORATION (JP) 1998-03-18 EP disclosed
WO-1996037451-A1 LIQUID CRYSTALLINE COMPOUNDS HAVING EXO-METHYLENE SITE AND LIQUID CRYSTAL COMPOSITIONS COMPRISING THE SAME CHISSO CORPORATION (JP) 1996-11-28 WO disclosed