Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.60 |
| ▸ | CDC25B | P30305 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668812 | 0.85 | NR4A1 (0.60) | PTPN1MEN1KMT2ARXFP1NR4A1 | |
| SCHEMBL29792669 | 0.85 | NR4A1 (0.60) | PTPN1MEN1KMT2ARXFP1NR4A1 | |
| SCHEMBL6914788 | 0.84 | NR4A1 (0.58) | PTPN1MEN1KMT2ARXFP1NR4A1 | |
| SCHEMBL6913891 | 0.84 | NR4A1 (0.58) | PTPN1MEN1KMT2ARXFP1NR4A1 | |
| SCHEMBL6916016 | 0.84 | NR4A1 (0.58) | PTPN1MEN1KMT2ARXFP1NR4A1 | |
| SCHEMBL6916066 | 0.84 | NR4A1 (0.58) | PTPN1MEN1KMT2ARXFP1NR4A1 | |
| SCHEMBL6914847 | 0.84 | NR4A1 (0.58) | PTPN1MEN1KMT2ARXFP1NR4A1 | |
| SCHEMBL14937023 | 0.84 | ALDH1A1 (0.61) | PTPN1MEN1KMT2ARXFP1KDM4E | |
| SCHEMBL21679499 | 0.84 | MEN1 (0.49) | PTPN1MEN1KMT2ARXFP1NR4A1 | |
| SCHEMBL6916021 | 0.84 | NR4A1 (0.58) | PTPN1MEN1KMT2ARXFP1NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902010-B1 | PROCESS FOR THE PREPARATION OF ADAPALENE AND RELATED COMPOUNDS | MEDICHEM SA (ES) | 2011-11-30 | — | — | EP | claimed |
| US-12590062-B2 | PD-1/PD-L1 inhibitors | GILEAD SCIENCES, INC. (US) | 2026-03-31 | — | — | US | disclosed |
| CN-118878461-A | PD-1/PD-L1 inhibitors | 吉利德科学公司 | 2024-11-01 | — | — | CN | disclosed |
| EP-4026835-A2 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2022-07-13 | — | — | EP | disclosed |
| EP-4026835-A2 | PD-1/PD-L1 INHIBITORS | Gilead Sciences, Inc. (US) | 2022-07-13 | — | — | EP | disclosed |
| EP-3612525-B1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-27 | — | — | EP | disclosed |
| EP-3612525-B1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-27 | — | — | EP | disclosed |
| US-20210323922-A1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2021-10-21 | — | — | US | disclosed |
| CN-110799509-A | PD-1/PD-L1 inhibitors | 吉利德科学公司 | 2020-02-14 | — | — | CN | disclosed |
| US-20180305315-A1 | PD-1/PD-L1 INHIBITORS | GILEAD SCIENCES, INC. | 2018-10-25 | — | — | US | disclosed |
| WO-2006108717-A2 | NEW METHOD FOR THE PREPARATION OF 6-(3-(1-ADAMANTYL)-4-METHOXPHENYL)-2-NAPHTHOIC ACID | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2006-10-19 | — | — | WO | disclosed |
| EP-0339887-B1 | Process for the preparation of indigo compounds | MITSUI TOATSU CHEMICALS (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5132421-A | 2-naphthyl-carbapenem intermediates | MERCK & CO., INC. (US) | 1992-07-21 | — | — | US | disclosed |
| US-5132422-A | 2-naphthyl-carbapenem intermediates | MERCK & CO., INC. (US) | 1992-07-21 | — | — | US | disclosed |
| EP-0466254-A1 | 2-naphthyl-carbapenems | MERCK & CO. INC. (US) | 1992-01-15 | — | — | EP | disclosed |
| US-5032587-A | Antibiotics, carbapenicillins | MERCK & CO., INC. (US) | 1991-07-16 | — | — | US | disclosed |
| US-5006519-A | 2-naphthyl-carbapenem antibacterial agents | MERCK & CO., INC. (US) | 1991-04-09 | — | — | US | disclosed |
| US-4973706-A | OXIDATION OF INDOLE WITH HYDROPEROXIDE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-11-27 | — | — | US | disclosed |
| CN-1037527-A | The preparation method of indigo compound | MITSUI TOATSU CHEMICALS (JP) | 1989-11-29 | — | — | CN | disclosed |
| EP-0339887-A1 | Process for the preparation of indigo compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210323922-A1 | PD-1/PD-L1 INHIBITORS | CD274, PDCD1, PDCD1LG2 | PTPN1 436/4885MEN1 1022/4885KMT2A 1628/4885 |
| US-12590062-B2 | PD-1/PD-L1 inhibitors | CD274, PDCD1LG2, PDCD1 | PTPN1 370/4885MEN1 3035/4885KMT2A 1216/4885 |
| US-20180305315-A1 | PD-1/PD-L1 INHIBITORS | CD274, PDCD1, PDCD1LG2 | PTPN1 436/4885MEN1 1022/4885KMT2A 1628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.