Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15285331 | 0.88 | CA14 (0.36) | NFKB1NFKB2RELACCR5SSTR4 | |
| SCHEMBL10323856 | 0.84 | CA14 (0.34) | NFKB1NFKB2RELASSTR4ASGR1 | |
| SCHEMBL1067463 | 0.83 | EPHX1 (0.36) | CA14HSD11B1 | |
| SCHEMBL1238808 | 0.82 | CA14 (0.33) | NFKB1NFKB2RELACCR5SSTR4 | |
| SCHEMBL2660690 | 0.82 | CA14 (0.33) | NFKB1NFKB2RELACCR5SSTR4 | |
| SCHEMBL13641157 | 0.82 | ASGR1 (0.33) | NFKB1NFKB2RELACCR5SSTR4 | |
| SCHEMBL10325232 | 0.82 | ASGR1 (0.33) | NFKB1NFKB2RELACCR5SSTR4 | |
| SCHEMBL20674336 | 0.81 | SLC6A4 (0.35) | CA14 | |
| SCHEMBL20673952 | 0.80 | GPR119 (0.36) | NFKB1NFKB2RELACCR5MT-CO2 | |
| SCHEMBL25447696 | 0.79 | PIK3CD (0.36) | NFKB1NFKB2RELACCR5GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |