⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12849273 | 0.91 | TSHR (0.48) | — | |
| SCHEMBL15365085 | 0.85 | — | — | |
| Acetone SCHEMBL9190129 | 0.85 | ALDH1A1 (0.56) | — | |
| SCHEMBL9925427 | 0.84 | TSHR (0.50) | — | |
| SCHEMBL19371288 | 0.83 | — | — | |
| Acetic Acid SCHEMBL4650595 | 0.83 | ALDH1A1 (0.54) | — | |
| Methyl Alcohol SCHEMBL8855368 | 0.82 | — | — | |
| Ethane SCHEMBL9809196 | 0.82 | — | — | |
| SCHEMBL25806 | 0.81 | — | — | |
| SCHEMBL1488043 | 0.81 | TSHR (0.65) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102327648-B | Porous magnesium alloy/biological ceramic bionic composite support and quick forming method thereof | UNIV XI AN JIAOTONG | 2013-08-14 | — | — | CN | claimed |
| CN-103071187-A | Ligament-bone composite scaffold with biomimetic connecting interface and forming method thereof | UNIV XI AN JIAOTONG | 2013-05-01 | — | — | CN | claimed |
| CN-102335460-A | Magnesium alloy/biological ceramic bone bracket based on photocuring and gel casting and forming method of bone bracket | UNIV XI AN JIAOTONG | 2012-02-01 | — | — | CN | claimed |
| CN-102327648-A | Porous magnesium alloy/biological ceramic bionic composite support and quick forming method thereof | UNIV XI AN JIAOTONG | 2012-01-25 | — | — | CN | claimed |
| CN-101148360-B | Customized forming method for gradient porous structure ceramic | UNIV XI AN JIAOTONG | 2010-05-19 | — | — | CN | claimed |
| CN-100528103-C | Bionic artificial semi-joint body and manufacturing technique thereof | UNIV XI AN JIAOTONG (CN) | 2009-08-19 | — | — | CN | claimed |
| CN-101148360-A | Customized forming method for gradient porous structure ceramic | UNIV XI AN JIAOTONG (CN) | 2008-03-26 | — | — | CN | claimed |
| CN-101108145-A | Bionic artificial semi- joint body and manufacturing technique thereof | UNIV XI AN JIAOTONG (CN) | 2008-01-23 | — | — | CN | claimed |
| CN-1234060-A | Use of polymer dispersions as binding agents for sealing compounds and coating compound | BASF AG (DE) | 1999-11-03 | — | — | CN | claimed |
| WO-2024086664-A2 | COVALENT INHIBITORS OF WILD-TYPE AND MUTANT PI3K AND METHOD OF USES THEREOF | TOTUS MEDICINES INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| WO-2023183936-A2 | COMBINATION THERAPY OF A PI3K INHIBITOR AND KRAS INHIBITOR AND METHODS OF USE THEREOF | TOTUS MEDICINES INC. (US) | 2023-09-28 | — | — | WO | disclosed |
| WO-2023135425-A1 | INHIBITORS OF TRANSGLUTAMINASE | ASTON UNIVERSITY (GB) | 2023-07-20 | — | — | WO | disclosed |
| US-11697793-B2 | Compositions and methods of making and using protein-functionalized hydrogels | WASHINGTON UNIVERSITY (US) | 2023-07-11 | — | — | US | disclosed |
| WO-2021055747-A1 | THERAPEUTIC CONJUGATES | TOTUS MEDICINES INC. (US) | 2021-03-25 | — | — | WO | disclosed |
| EP-0837112-A2 | Cross-linkable, electrically conductive composition, electric conductor and process for forming the same | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-04-22 | — | — | EP | disclosed |
| EP-0505972-B1 | Process for producing styrenic copolymer | IDEMITSU KOSAN CO (JP) | 1997-06-11 | — | — | EP | disclosed |
| EP-0490269-B1 | Graft copolymer and process for producing the same | IDEMITSU KOSAN CO (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5250629-A | Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts | IDEMITSU KOSAN CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0505972-A2 | Process for producing styrenic copolymer | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-09-30 | — | — | EP | disclosed |
| EP-0490269-A1 | Graft copolymer and process for producing the same | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-06-17 | — | — | EP | disclosed |