SCHEMBL8219008

SCHEMBL8219008

c1ccc(NC[SiH2]c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
MAPT P10636 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
IDO1 P14902 1/20 0.40
HTT P42858 1/20 0.40
HSD17B10 Q99714 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
CTSD P07339 1/20 0.38
CA12 O43570 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
DNM1 Q05193 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
FFAR1 O14842 1/20 0.36
TSHR P16473 2/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2270138 0.73 KDM4E (0.41) ALDH1A1MAPTL3MBTL1TSHRMAPK1
SCHEMBL29901837 0.73 ALDH1A1 (0.48) ALDH1A1MAPTL3MBTL1HTTHSD17B10
SCHEMBL2274476 0.70 KCNN4 (0.35) HTTTDP1TP53
SCHEMBL10359187 0.70 MAPT (0.44) ALDH1A1MAPTL3MBTL1HTTHSD17B10
SCHEMBL178138 0.69
SCHEMBL9510289 0.69
SCHEMBL7277860 0.68 MAPT (0.68) ALDH1A1MAPTL3MBTL1SMN1; SMN2HTT
SCHEMBL8217604 0.68
SCHEMBL10649815 0.68 MEN1 (0.60) MAPTIDO1TDP1MAOACYP3A4
SCHEMBL232188 0.68 MAPT (0.78) ALDH1A1MAPTL3MBTL1IDO1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136995-A Process for producing aminosilane compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-24 US disclosed