Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 10/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8213776 | 0.90 | CA12 (0.48) | PIK3CDPIK3CACA12CA1CA2 | |
| SCHEMBL11924776 | 0.87 | PIK3CD (0.45) | PIK3CDPIK3CACA12CA1CA2 | |
| SCHEMBL8214220 | 0.84 | PIK3CA (0.48) | PIK3CDPIK3CAALDH1A1MTOR | |
| SCHEMBL8214526 | 0.84 | PIK3CD (0.61) | PIK3CDPIK3CAGHSRMTOR | |
| SCHEMBL11925866 | 0.83 | PIK3CA (0.48) | PIK3CDPIK3CACA12CA1CA2 | |
| SCHEMBL8214174 | 0.82 | PIK3CD (0.49) | PIK3CDPIK3CACA12CA1CA2 | |
| SCHEMBL8206578 | 0.82 | PIK3CD (0.46) | PIK3CDPIK3CAALDH1A1LMNA | |
| SCHEMBL8216529 | 0.82 | PIK3CD (0.53) | PIK3CDPIK3CAGHSRMTOR | |
| SCHEMBL8216930 | 0.81 | PIK3CD (0.50) | PIK3CDPIK3CACA12CA1CA2 | |
| SCHEMBL8215123 | 0.81 | NAMPT (0.55) | PIK3CDPIK3CAALDH1A1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023159-A1 | MORPHOLINO PYRIMIDINE DERIVATIVES USEFUL IN THE TREATMENT OF PROLIFERATIVE DISORDERS | ASTRAZENECA AB (SE) | 2008-02-28 | — | — | WO | disclosed |