Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 10/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3035668 | 0.90 | PRKAA2 (0.58) | PRKAA2HRH3PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL3138233 | 0.85 | PRKAA2 (0.53) | PRKAA2HRH3MAPK14KCNQ3KCNQ2 | |
| SCHEMBL3129054 | 0.83 | PRKAA2 (0.51) | PRKAA2MAPK14KCNQ3KCNQ2KCNE1 | |
| SCHEMBL3143111 | 0.83 | PRKAA2 (0.50) | PRKAA2HRH3KCNQ3KCNQ2KCNE1 | |
| Hydrochloric Acid SCHEMBL3133196 | 0.82 | PRKAA2 (0.50) | PRKAA2MAPK14KCNQ3KCNQ2KCNE1 | |
| SCHEMBL12094954 | 0.81 | SMN1; SMN2 (0.40) | PRKAA2KCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL3147307 | 0.81 | MEN1 (0.57) | PRKAA2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3139468 | 0.81 | PRKAA2 (0.53) | PRKAA2HRH3PRKAB2PRKAG1PRKAA1 | |
| SCHEMBL3147389 | 0.80 | MEN1 (0.57) | PRKAA2MEN1KMT2A | |
| Bromide SCHEMBL3051765 | 0.79 | STAT3 (0.49) | PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236826-B2 | Diarylether derivatives as antitumor agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-08-07 | — | — | US | claimed |
| US-8188277-B2 | Aromatic compounds for suppressing the generation of collagen | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-05-29 | — | — | US | claimed |