SCHEMBL3035668

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3143111	0.93	PRKAA2 (0.50)	PRKAA2FAAHHRH3OPRM1OPRD1
	SCHEMBL8220138	0.90	PRKAA2 (0.57)	PRKAA2HRH3SMN1; SMN2PRKAB2PRKAG1
	SCHEMBL3139468	0.87	PRKAA2 (0.53)	PRKAA2PKMMAPK1FAAHHRH3
	SCHEMBL3138310	0.86	MEN1 (0.51)	PRKAA2FAAHHRH3
	SCHEMBL3030079	0.86	PRKAA2 (0.63)	PRKAA2GAASMN1; SMN2LMNAPRKAB2
	SCHEMBL3138233	0.86	PRKAA2 (0.53)	PRKAA2MAPK1HRH3ALDH1A1GAA
	SCHEMBL3031846	0.85	MAPT (0.48)	PRKAA2MAPK1FAAHSMN1; SMN2KDM4E
	Hydrochloric Acid SCHEMBL3137931	0.85	NOD1 (0.47)	PRKAA2FAAHHRH3ALDH1A1GAA
	SCHEMBL3129054	0.84	PRKAA2 (0.51)	PRKAA2SMN1; SMN2KDM4E
	SCHEMBL3139083	0.83	PRKAA2 (0.58)	PRKAA2HRH3GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.