Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | CFD | P00746 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | COL1A1 | P02452 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104352 | 1.00 | F10 (0.42) | F10CFDKDM4EMEN1KMT2A | |
| SCHEMBL12371503 | 0.91 | F10 (0.41) | F10CFDKDM4EMEN1KMT2A | |
| SCHEMBL12101411 | 0.89 | F10 (0.45) | F10CFDKLKB1 | |
| SCHEMBL12371502 | 0.86 | F10 (0.41) | F10CFDKDM4EMEN1KMT2A | |
| SCHEMBL8222128 | 0.86 | F10 (0.43) | F10CFDKDM4EMEN1KMT2A | |
| SCHEMBL12101392 | 0.86 | F10 (0.43) | F10CFDKDM4EMEN1KMT2A | |
| SCHEMBL12892314 | 0.86 | F10 (0.43) | F10CFDKDM4EMEN1KMT2A | |
| SCHEMBL13104233 | 0.83 | F10 (0.42) | F10CFDKDM4EMEN1KMT2A | |
| SCHEMBL12101402 | 0.83 | F10 (0.51) | F10CFDKLKB1TSHR | |
| SCHEMBL12101303 | 0.83 | F10 (0.52) | F10CFDKLKB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007131982-A2 | SUBSTITUTED PROLINAMIDES, PRODUCTION THEREOF AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-11-22 | — | — | WO | disclosed |