Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 4/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | DRD3 | P35462 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9750973 | 0.85 | L3MBTL1 (0.74) | TSHRDRD4DRD2DRD3L3MBTL1 | |
| SCHEMBL3892463 | 0.84 | CHRNA7 (0.72) | TSHRDRD4DRD2DRD3L3MBTL1 | |
| Hydrochloric Acid SCHEMBL29686987 | 0.83 | L3MBTL1 (0.67) | TSHRDRD4DRD2DRD3L3MBTL1 | |
| SCHEMBL8219883 | 0.81 | SLC18A3 (0.60) | TSHRKDM4ESLC18A3 | |
| SCHEMBL13898514 | 0.80 | ABCB1 (0.57) | TSHRL3MBTL1KDM4ECYP2D6HIF1A | |
| SCHEMBL13898309 | 0.80 | ABCB1 (0.57) | TSHRL3MBTL1KDM4ECYP2D6HIF1A | |
| SCHEMBL13515653 | 0.79 | DRD4 (0.62) | TSHRDRD4DRD2DRD3L3MBTL1 | |
| SCHEMBL3038609 | 0.79 | DRD4 (0.62) | TSHRDRD4DRD2DRD3L3MBTL1 | |
| SCHEMBL13515649 | 0.79 | TSHR (0.47) | TSHRDRD4KCNH2 | |
| SCHEMBL3043127 | 0.79 | TSHR (0.47) | TSHRDRD4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |