Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 10/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 8/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.39 |
| ▸ | ITGAL | P20701 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12844640 | 0.88 | CACNA1H (0.49) | CACNA1HMDM2TP53 | |
| SCHEMBL12844637 | 0.88 | CACNA1H (0.43) | CACNA1HITGB2ICAM1ITGAL | |
| SCHEMBL8210807 | 0.85 | CACNA1H (0.47) | CACNA1HMDM2TP53 | |
| SCHEMBL8209942 | 0.78 | HSD11B1 (0.50) | CACNA1H | |
| SCHEMBL8229542 | 0.77 | CACNA1H (0.71) | CACNA1HMDM2 | |
| SCHEMBL3998065 | 0.76 | CACNA1H (0.66) | CACNA1H | |
| SCHEMBL8201959 | 0.76 | CACNA1H (0.62) | CACNA1H | |
| SCHEMBL12890364 | 0.73 | CACNA1H (0.40) | CACNA1H | |
| SCHEMBL8212780 | 0.73 | CACNA1H (0.53) | CACNA1HMDM2TP53 | |
| SCHEMBL12777757 | 0.71 | HSD11B1 (0.50) | CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033468-A2 | AZETIDINE AND AZETIDONE DERIVATIVES USEFUL IN TREATING PAIN AND DISORDERS OF LIPID METABOLISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |