SCHEMBL8221

SCHEMBL8221

CCCCCCCCCCCCCCC[C]=O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
THRB P10828 1/20 0.50
PTPN7 P35236 4/20 0.44
HMGCR P04035 2/20 0.44
RECQL P46063 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
EPHX2 P34913 1/20 0.39
ALDH1A1 P00352 2/20 0.38
DNM1 Q05193 1/20 0.38
LMNA P02545 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18911577 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL157361 1.00
SCHEMBL1332658 1.00
SCHEMBL154927 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL15978 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL4879841 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL9234866 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL177432 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL371425 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL6942814 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 66196 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024149215-A1 DESIGNED PEPTIDE, AND COMPOSITION AND USE THEREOF 深圳市维琪科技股份有限公司 2024-07-18 WO claimed
US-20240238390-A1 PEPTIDES FOR THE TREATMENT OF CANCER AND/OR METASTASIS BCN PEPTIDES, S.A. (ES) 2024-07-18 US claimed
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 US claimed
US-20240238186-A1 Topical Compositions Comprising (Glyco)Sphingolipids and/or (Glyco)Ceramides CARBOCODE S.A. (PT) 2024-07-18 US claimed
EP-4400508-A1 ACTIVE PEPTIDE AND USE THEREOF Harvest Biotech Co., Ltd (CN) 2024-07-17 EP claimed
EP-3558264-B1 OPHTALMOLOGIC PREPARATION CONTIPRO AS (CZ) 2024-07-17 EP claimed
US-12036263-B2 Topical compositions ILLUSTRIS PHARMACEUTICALS, INC. (US) 2024-07-16 US claimed
CN-114423398-B Surface treatment method for powder, surface treatment agent composition used therein, and surface-treated powder 味之素株式会社 2024-07-16 CN claimed
CN-115844775-B Essence with efficacy of lifting, tightening and inducing 上海悦目化妆品有限公司 2024-07-16 CN claimed
CN-118320054-A Antiviral disinfectant for medical care products and preparation method thereof 中国人民解放军陆军军医大学第一附属医院 2024-07-12 CN claimed
US-4070458-A MICRBIAL ENZYME SANRAKU-OCEAN CO., LTD. (JA) 1978-01-24 US claimed
US-4055468-A TETRAPEPTIDE SANRAKU-OCEAN CO., LTD. (JA) 1977-10-25 US claimed
US-4055716-A NUCLEOSIDE, ANTILEUKEMIA ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1977-10-25 US claimed
US-3998807-A ARABINOFURANOSYL CYTOSINES AND METHODS OF MAKING SYNTEX (U.S.A.) INC. (US) 1976-12-21 US claimed
US-3991186-A ANTIINFLAMMATORY AGENTS NIPPON SHINYAKU CO., LTD. (JA) 1976-11-09 US claimed
US-3991045-A ANTICARCINOGENIC AND ANTITUMOR AGENT, INSECTICIDES, FUNGICIDAL SURFACTANT ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-11-09 US claimed
US-3975367-A PEPTIDE, VIRICIDE, IMMUNOSUPPRESSANT, NEOPLASTIC CELLS THE UPJOHN COMPANY (US) 1976-08-17 US claimed
US-3960836-A Acylated derivatives of pyrazofurin and process for their preparation ELI LILLY AND COMPANY (US) 1976-06-01 US claimed
US-3951964-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-04-20 US claimed
US-3943132-A Process for the preparation of hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed