SCHEMBL1696132

SCHEMBL1696132

CCCCCCCCCCCCCCCCCCCCCCCCCCC[C]=O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.50
▸ THRB P10828 1/20 0.50
▸ PTPN7 P35236 4/20 0.44
▸ HMGCR P04035 2/20 0.44
▸ RECQL P46063 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ CES2 O00748 3/20 0.39
▸ CES1 P23141 3/20 0.39
▸ EPHX2 P34913 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ DNM1 Q05193 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9309385 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL1696121 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL9697065 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL18911586 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL15416 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL120107 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL44157 1.00 — —
SCHEMBL74679 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL4874844 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL
SCHEMBL17090795 1.00 TSHR (0.50) TSHRTHRBPTPN7HMGCRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110283223-B Cationic lipid molecule and application thereof in nucleic acid delivery 广州市锐博生物科技有限公司 2022-01-04 — — CN claimed
US-20080044462-A1 STABILIZED TRANSDERMAL BUPROPION PREPARATIONS COLLEGIUM PHARMACEUTICAL, INC. DELAWARE 2008-02-21 — — US claimed
WO-2007117581-A2 STABILIZED TRANSDERMAL BUPROPION PREPARATIONS COLLEGIUM PHARMACEUTICAL, INC. (US) 2007-10-18 — — WO claimed
US-20070116757-A1 Methylene Blue Derivatives COLLEGIUM PHARMACEUTICAL, INC. 2007-05-24 — — US claimed
WO-2007056439-A1 SALTS OF METHYLENE BLUE AND ITS DERIVATIVES COLLEGIUM PHARMACEUTICAL, INC. (US) 2007-05-18 — — WO claimed
WO-1999010359-A2 LIPOSOMIC BASED SIALYL LEWIS X MIMETICS NOVARTIS AG (CH) 1999-03-04 — — WO claimed
EP-0688555-A2 Hair-growing agent TANABE SEIYAKU CO., LTD. (JP) 1995-12-27 — — EP claimed
US-20240009092-A1 COSMETIC COMPOSITION AND COSMETIC QUASI-DRUG INCLUDING LIPID PARTICLES CONTAINING PHOSPHOLIPID NIPPON SHOKUBAI CO., LTD. (JP) 2024-01-11 — — US disclosed
WO-2023238859-A1 COATED PARTICLES FOR COSMETIC 三洋化成工業株式会社 2023-12-14 — — WO disclosed
WO-2023238837-A1 EXOSOME COMPLEX AND MANUFACTURING METHOD THEREOF JSR株式会社 2023-12-14 — — WO disclosed
CN-110283223-B Cationic lipid molecule and application thereof in nucleic acid delivery 广州市锐博生物科技有限公司 2022-01-04 — — CN disclosed
US-10745669-B2 Culture method for stable proliferation of pluripotent stem cell while maintaining undifferentiated state AJINOMOTO CO., LTD. (JP) 2020-08-18 — — US disclosed
US-10662411-B2 Culture method for stable proliferation of pluripotent stem cell while maintaining undifferentiated state AJINOMOTO CO., INC. (JP) 2020-05-26 — — US disclosed
EP-0604945-A1 TAN-1511, its derivatives, production and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-07-06 — — EP disclosed
EP-0604957-A1 2-Amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-07-06 — — EP disclosed
EP-0517262-A1 Trifluorothymidine derivatives, process for producing the same and anti-cancer agent containing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-12-09 — — EP disclosed
EP-0503508-A1 Vesicles and polymeric vesicles Kao Corporation (JP) 1992-09-16 — — EP disclosed
EP-0094804-B1 GLUCOSAMINYL MURAMYL PEPTIDE DERIVATIVES Dainippon Pharmaceutical Co., Ltd. (JP) 1985-11-13 — — EP disclosed
US-4545932-A NONSPECIFIC RESISTANCE TO MICROBIAL INFECTIONS, IMMUNOSTIMULANTS DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1985-10-08 — — US disclosed
EP-0094804-A1 Glucosaminyl muramyl peptide derivatives Dainippon Pharmaceutical Co., Ltd. (JP) 1983-11-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240009092-A1 COSMETIC COMPOSITION AND COSMETIC QUASI-DRUG INCLUDING LIPID PARTICLES CONTAINING PHOSPHOLIPID PLIN5, PHOSPHO1, PLIN3 TSHR 1575/4885THRB 3096/4885PTPN7 514/4885
US-20070116757-A1 Methylene Blue Derivatives ACMSD, SI, HTR2B TSHR 4306/4885THRB 3056/4885PTPN7 4473/4885
US-20080044462-A1 STABILIZED TRANSDERMAL BUPROPION PREPARATIONS BDNF, FFAR4, FFAR2 TSHR 1885/4885THRB 1535/4885PTPN7 2516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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