Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | KIT | P10721 | 3/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4137706 | 0.90 | DPP4 (0.47) | DPP4DPP8KITPDGFRBENPP1 | |
| SCHEMBL3928397 | 0.86 | DPP4 (0.45) | DPP4DPP8PDGFRBENPP1 | |
| SCHEMBL3924048 | 0.83 | DPP4 (0.46) | DPP4DPP8ENPP1 | |
| SCHEMBL3920145 | 0.81 | DPP4 (0.49) | DPP4DPP8 | |
| SCHEMBL3922240 | 0.77 | DPP4 (0.34) | DPP4DPP8KITPDGFRB | |
| SCHEMBL3919096 | 0.77 | DPP4 (0.48) | DPP4DPP8KITPDGFRBENPP1 | |
| SCHEMBL3923064 | 0.72 | DPP4 (0.48) | DPP4DPP8KIT | |
| SCHEMBL3923067 | 0.72 | DPP4 (0.48) | DPP4DPP8KIT | |
| SCHEMBL3930794 | 0.66 | KIT (0.45) | DPP4DPP8KITPDGFRB | |
| SCHEMBL3930801 | 0.66 | KIT (0.45) | DPP4DPP8KITPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007148185-A2 | SUBSTITUTED 3 -AMINO- PYRROLIDINO-4 -LACTAMS AS DPP INHIBITORS | PFIZER PRODUCTS INC. (US) | 2007-12-27 | — | — | WO | disclosed |