Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 2/20 | 0.45 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.45 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.45 |
| ▸ | LIPC | P11150 | 6/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4513765 | 0.89 | PRKD3 (0.51) | PRKD3PRKD1PRKD2LIPCLIPG | |
| SCHEMBL4513754 | 0.89 | PRKD3 (0.51) | PRKD3PRKD1PRKD2LIPCLIPG | |
| SCHEMBL4513736 | 0.89 | PRKD3 (0.51) | PRKD3PRKD1PRKD2LIPCLIPG | |
| SCHEMBL4508519 | 0.75 | PRKD3 (0.67) | PRKD3PRKD1PRKD2MAP4K4WNT1 | |
| SCHEMBL4508525 | 0.75 | PRKD3 (0.67) | PRKD3PRKD1PRKD2MAP4K4WNT1 | |
| SCHEMBL4508530 | 0.75 | PRKD3 (0.67) | PRKD3PRKD1PRKD2MAP4K4WNT1 | |
| SCHEMBL4520418 | 0.68 | PRKD3 (0.51) | PRKD3PRKD1PRKD2MAPK1MAPT | |
| SCHEMBL4520412 | 0.68 | PRKD3 (0.51) | PRKD3PRKD1PRKD2MAPK1MAPT | |
| SCHEMBL4520417 | 0.68 | PRKD3 (0.51) | PRKD3PRKD1PRKD2MAPK1MAPT | |
| SCHEMBL4514171 | 0.64 | PRKD3 (0.45) | PRKD3PRKD1PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007125331-A2 | AMINO-ETHYL-AMINO-ARYL (AEAA) COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-11-08 | — | — | WO | disclosed |