Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9782674 | 0.84 | SMN1; SMN2 (0.36) | MEP1BMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL778370 | 0.84 | SMN1; SMN2 (0.41) | MEP1BMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL9702364 | 0.84 | SMN1; SMN2 (0.38) | MEP1BMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL777012 | 0.83 | MEN1 (0.34) | MEP1BMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL777059 | 0.81 | SMN1; SMN2 (0.39) | MEP1BMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL775800 | 0.80 | SMN1; SMN2 (0.40) | MEP1BMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL776652 | 0.80 | FFAR4 (0.40) | MEN1ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL16975313 | 0.80 | SMN1; SMN2 (0.40) | MEP1BMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL777271 | 0.80 | SMN1; SMN2 (0.38) | MEP1BMEN1ALDH1A1KMT2AGAA | |
| SCHEMBL778146 | 0.78 | SMN1; SMN2 (0.41) | MEP1BMEN1ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078724-A2 | IMIDAZOLINDERIVATIVES THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |
| WO-1992000402-A2 | AZEOTROPE-LIKE COMPOSITIONS OF DICHLOROPENTAFLUOROPROPANE, 2-PROPANOL AND A HYDROCARBON CONTAINING SIX CARBON ATOMS | ALLIED-SIGNAL INC. (US) | 1992-01-09 | — | — | WO | disclosed |