SCHEMBL9702364

SCHEMBL9702364

Cc1ccc(S(=O)(=O)O)c(C(F)(F)C(C)(F)F)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.38
GAA P10253 2/20 0.35
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
RECQL P46063 1/20 0.35
CASP6 P55212 1/20 0.35
ELAVL1 Q15717 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
HSD17B10 Q99714 1/20 0.34
HSD17B2 P37059 2/20 0.33
MPL P40238 1/20 0.33
MCL1 Q07820 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA5A P35218 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL778370 0.90 SMN1; SMN2 (0.41) SMN1; SMN2GAAMEN1ALDH1A1KMT2A
SCHEMBL777059 0.87 SMN1; SMN2 (0.39) SMN1; SMN2GAAMEN1ALDH1A1KMT2A
SCHEMBL16975313 0.86 SMN1; SMN2 (0.40) SMN1; SMN2GAAMEN1ALDH1A1KMT2A
SCHEMBL775800 0.86 SMN1; SMN2 (0.40) SMN1; SMN2GAAMEN1ALDH1A1KMT2A
SCHEMBL776652 0.86 FFAR4 (0.40) SMN1; SMN2GAAMEN1ALDH1A1KMT2A
SCHEMBL777271 0.85 SMN1; SMN2 (0.38) SMN1; SMN2GAAMEN1ALDH1A1KMT2A
SCHEMBL8222006 0.84 MEP1B (0.35) SMN1; SMN2GAAMEN1ALDH1A1KMT2A
SCHEMBL778146 0.83 SMN1; SMN2 (0.41) SMN1; SMN2GAAMEN1ALDH1A1KMT2A
SCHEMBL9782674 0.80 SMN1; SMN2 (0.36) SMN1; SMN2GAAMEN1ALDH1A1KMT2A
SCHEMBL4371287 0.79 GAA (0.35) SMN1; SMN2GAAMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992011400-A1 AZEOTROPE-LIKE COMPOSITIONS OF DICHLOROPENTAFLUOROPROPANE, AN ALKANOL HAVING 1-3 CARBON ATOMS AND 2-METHYL-2-PROPANOL ALLIED-SIGNAL INC. (US) 1992-07-09 WO disclosed