SCHEMBL822221

SCHEMBL822221

OCCCCC(O)OC(O)CCCCO

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 2/20 0.30
ALDH1A1 P00352 1/20 0.30
HSD17B10 Q99714 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27541552 0.97 LMNA (0.35) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL2043878 0.91 TSHR (0.38) TSHRTHRB
Water SCHEMBL10834803 0.88 TSHR (0.36) TSHRTHRB
1,4-Butanediol SCHEMBL5880631 0.86 LMNA (0.56) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL7880865 0.85 SMN1; SMN2 (0.32) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL27798642 0.83
SCHEMBL7526967 0.83 LMNA (0.35) TSHRSMN1; SMN2LMNAALDH1A1HSD17B10
SCHEMBL1002494 0.81 LMNA (0.33) TSHRLMNAALDH1A1HSD17B10MEN1
SCHEMBL1428654 0.78 LMNA (0.33) TSHRLMNAALDH1A1HSD17B10MEN1
SCHEMBL12349192 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 642 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6340738-B2 ESTER INTERCHANGE; CRYSTALLIZATION GENERAL ELECTRIC COMPANY 2002-01-22 US claimed
EP-0028353-B2 PROCESS FOR PRODUCING AN AROMATIC POLYESTERPOLYCARBONATE MITSUBISHI KASEI CORPORATION (JP) 1987-12-23 EP claimed
EP-0028353-B1 PROCESS FOR PRODUCING AN AROMATIC POLYESTERPOLYCARBONATE MITSUBISHI KASEI CORPORATION (JP) 1983-09-07 EP claimed
US-4369303-A Process for producing an aromatic polyesterpolycarbonate MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1983-01-18 US claimed
EP-0028353-A1 Process for producing an aromatic polyesterpolycarbonate MITSUBISHI KASEI CORPORATION (JP) 1981-05-13 EP claimed
EP-2987829-B2 POLYCARBONATE-TYPE RESIN COMPOSITION AND MOLDED ARTICLE IDEMITSU KOSAN CO (JP) 2024-07-17 EP disclosed
US-12024629-B2 Polycarbonate-based resin, production method therefor, and polycarbonate-based resin composition IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
US-20240199849-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLES IDEMITSU KOSAN CO.,LTD. (JP) 2024-06-20 US disclosed
US-20240150574-A1 POLYCARBONATE RESIN COMPOSITION IDEMITSU KOSAN CO.,LTD. (JP) 2024-05-09 US disclosed
WO-2024090157-A1 POLYCARBONATE RESIN AND MOLDED ARTICLE FORMED OF SAME 帝人株式会社 2024-05-02 WO disclosed
EP-4350057-A1 THERMOPLASTIC RESIN COMPOSITION, METHOD FOR PRODUCING SHAPED BODY, SHAPED BODY AND USE OF RESIN MATERIAL ADEKA CORPORATION (JP) 2024-04-10 EP disclosed
CN-117836121-A Thermoplastic resin composition, method for producing molded body, and molded body 株式会社艾迪科 2024-04-05 CN disclosed
US-5142018-A Process for preparing polycarbonates GE PLASTICS JAPAN LTD. (JP) 1992-08-25 US disclosed
US-5041523-A Interfacial polycondensation using divalent phenol and branching agent IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1991-08-20 US disclosed
EP-0435124-A2 Processes for preparing aromatic polycarbonates GE PLASTICS JAPAN LIMITED (JP) 1991-07-03 EP disclosed
EP-0434998-A2 Polycarbonate or polyestercarbonate resin compositions and preparing methods thereof GE PLASTICS JAPAN LIMITED (JP) 1991-07-03 EP disclosed
US-5026817-A Melt condensation of aromatic dihydroxy compound and carbonic acid diester with catalyst of nitrogen component, boric acid or ester, and alkali or alkaline earth metal component; nonyellowing GE PLASTICS JAPAN, LTD. (JP) 1991-06-25 US disclosed
EP-0387714-A2 Process for production of branched polycarbonate IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1990-09-19 EP disclosed
EP-0360578-A2 Process for the production of polycarbonates GE PLASTICS JAPAN LTD. (JP) 1990-03-28 EP disclosed
EP-0351168-A2 Process for preparing polycarbonates GE PLASTICS JAPAN LTD. (JP) 1990-01-17 EP disclosed