Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15826976 | 0.93 | MAPT (0.50) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL16411295 | 0.88 | MAPT (0.50) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL11880082 | 0.88 | MAPT (0.50) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL11694639 | 0.87 | MAPT (0.46) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL23914101 | 0.84 | MAPT (0.47) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL21835380 | 0.84 | MAPT (0.47) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL23914112 | 0.84 | MAPT (0.47) | MAPTMGAMGAASIMGAM2 | |
| SCHEMBL822396 | 0.84 | MAPT (0.67) | MAPTMAPK1TSHRHSD17B10LMNA | |
| SCHEMBL822223 | 0.84 | — | — | |
| SCHEMBL14566774 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323016-A1 | AMBIENT TEMPERATURE CURABLE COATING AND USES THEREIN | WASHINGTON STATE UNIVERSITY | 2023-10-12 | — | — | US | disclosed |
| US-11155675-B2 | Method of regioselective synthesis of polyesters from asymmetric diols | VERSALIS S.P.A. (IT) | 2021-10-26 | — | — | US | disclosed |
| CN-109689727-B | Process for the regioselective synthesis of polyesters from asymmetric diols | 维尔萨利斯股份公司 | 2020-12-01 | — | — | CN | disclosed |
| CN-101410378-B | Malonamide derivatives as gamma secretase inhibitors | HOFFMANN LA ROCHE | 2012-12-05 | — | — | CN | disclosed |
| CN-101072760-B | Malonamide derivatives as gamma-secretase inhibitors for the treatment of Alzheimer's disease | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-28 | — | — | CN | disclosed |
| US-20110287102-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-11-24 | — | — | US | disclosed |
| CN-101410378-A | Malonamide derivatives as gamma secretase inhibitors | HOFFMANN LA ROCHE (CH) | 2009-04-15 | — | — | CN | disclosed |
| CN-101072760-A | Malonamide derivatives as gamma-secretase inhibitors for the treatment of Alzheimer's disease | HOFFMANN LA ROCHE (CH) | 2007-11-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | UMPS, PUF60, SMCHD1 | MAPT 826/4885MGAM 1033/4885GAA 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.