SCHEMBL822246

SCHEMBL822246

CC(O)COC(=O)CCCC(=O)OCC(C)O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.74
LMNA P02545 2/20 0.48
KDM4E B2RXH2 1/20 0.48
DUSP3 P51452 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.46
ATM Q13315 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
LPAR6 P43657 1/20 0.42
LPAR1 Q92633 1/20 0.42
LPAR4 Q99677 1/20 0.42
LPAR5 Q9H1C0 1/20 0.42
LPAR2 Q9HBW0 1/20 0.42
LPAR3 Q9UBY5 1/20 0.42
ENPP2 Q13822 1/20 0.42
PRKCA P17252 3/20 0.42
PRKCE Q02156 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL821850 0.95 MAPT (0.81) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL822169 0.93 MAPT (0.85) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL821856 0.93 MAPT (0.85) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL821851 0.93 MAPT (0.85) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL822254 0.93 MAPT (0.85) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL18411660 0.92 MAPT (0.65) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL10893020 0.92 MAPT (0.65) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL822396 0.90 MAPT (0.67) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL10403567 0.89 MAPT (0.85) MAPTLMNAKDM4EDUSP3MEN1
SCHEMBL1245287 0.87 MAPT (0.96) MAPTLMNAKDM4EDUSP3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155675-B2 Method of regioselective synthesis of polyesters from asymmetric diols VERSALIS S.P.A. (IT) 2021-10-26 US disclosed
CN-109689727-B Process for the regioselective synthesis of polyesters from asymmetric diols 维尔萨利斯股份公司 2020-12-01 CN disclosed
US-20110287102-A1 CHAIN EXTENDERS POLYNOVO BIOMATERIALS PTY LIMITED (AU) 2011-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110287102-A1 CHAIN EXTENDERS UMPS, PUF60, SMCHD1 MAPT 826/4885LMNA 570/4885KDM4E 1903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.