Uric Acid

Uric Acid

SCHEMBL822247

NC(N)=O.O=c1[nH]c(=O)c2[nH]c(=O)[nH]c2[nH]1

nearest known ligand 0.76

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 2/20 0.76
ALDH1A1 P00352 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
CYP2C19 P33261 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MAPT P10636 3/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39
BRPF1 P55201 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TYMP P19971 7/20 0.36
JAK2 O60674 1/20 0.34
THRB P10828 1/20 0.34
GSK3B P49841 1/20 0.34
BACE1 P56817 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uric Acid SCHEMBL8330954 0.91 GDA (0.70) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL17185561 0.88 GDA (0.80) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL22069923 0.87 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL30062557 0.87 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL7933 0.87 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL3417988 0.87 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL1331321 0.87 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL30173440 0.86 GDA (0.76) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL1893296 0.86 GDA (0.76) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL2434620 0.85 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3137201-B1 POROUS ASYMMETRIC POLYPHENYLENE ETHER MEMBRANES AND ASSOCIATED SEPARATION MODULES AND METHODS SHPP GLOBAL TECH BV (NL) 2023-10-11 EP disclosed
CN-116448990-A Sheath liquid for analyzing urinary sediment 中夏医学科技(青岛)有限公司 2023-07-18 CN disclosed
US-20230050412-A1 MEDICAL DIAGNOSTIC DEVICE BILKENT UNIVERSITESI (UNAM) ULUSAL NANOTEKNOLOJI ARASTIRMA MERKEZI (TR) 2023-02-16 US disclosed
CN-215606925-U Absorption core with high absorption effect 贵州卡布国际生物科技有限公司 2022-01-25 CN disclosed
CN-215606924-U Absorption core with excellent absorption performance 贵州卡布国际生物科技有限公司 2022-01-25 CN disclosed
CN-113384403-A Urine adsorption material and contain absorption core of this urine adsorption material 贵州卡布国际生物科技有限公司 2021-09-14 CN disclosed
CN-113384403-A Urine adsorption material and contain absorption core of this urine adsorption material 贵州卡布国际生物科技有限公司 2021-09-14 CN disclosed
CN-111514241-B Traditional Chinese medicine composition for treating female hyperplasia of mammary glands and preparation method thereof 内蒙古自治区中医医院 2021-09-07 CN disclosed
CN-109092047-B Microbial deodorization device for air-flush toilet 上海交通大学 2021-09-07 CN disclosed
WO-2021137829-A1 A MEDICAL DIAGNOSTIC DEVICE BILKENT UNIVERSITESI (UNAM) ULUSAL NANOTEKNOLOJI ARASTIRMA MERKEZI (TR) 2021-07-08 WO disclosed
WO-2015148943-A1 PREPARATION OF SMALL COLONY VARIANTS OF THERAPEUTIC BACTERIA CONJUGON, INC. (US) 2015-10-01 WO disclosed
US-9050061-B2 Health care device with a sample capture system to evaluate a health condition EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-06-09 US disclosed
CN-104114705-A Nucleic acid comprising or encoding a histone stem-loop and a polyadenylation sequence or polyadenylation signal for increasing the expression of an encoded therapeutic protein CUREVAC GMBH 2014-10-22 CN disclosed
US-20110054273-A1 HEALTH CARE DEVICE KRI INCORPORATION (JP) 2011-03-03 US disclosed
CN-100493705-C Swollen vermiculite loading NiB amorphous alloy catalyst preparation method and application UNIV NANKAI (CN) 2009-06-03 CN disclosed
CN-101045893-A Negative ion washing powder WU XIAN (CN) 2007-10-03 CN disclosed
CN-101015804-A Swollen vermiculite loading NiB amorphous alloy catalyst, its prepn. method and application UNIV NANKAI (CN) 2007-08-15 CN disclosed
US-4952582-A Pyrazinoylguanidine and derivatives thereof having few polar substituents and being useful as hyperuretic agents BEYER JR KARL H (US) 1990-08-28 US disclosed
US-4594349-A Containing a pyrimidine ring BEYER JR KARL H (US) 1986-06-10 US disclosed
US-3962158-A HYDROPHILIC POLYMER MEMBRANES OF POLYVINYL ALCOHOL AND CHITOSAN DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JA) 1976-06-08 US disclosed