SCHEMBL822271

SCHEMBL822271

O=C(CO)OCCOCCO

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
TSHR P16473 6/20 0.50
MAPK1 P28482 2/20 0.50
ALDH1A1 P00352 5/20 0.39
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPT P10636 2/20 0.38
THRB P10828 1/20 0.38
HTT P42858 1/20 0.38
EPHX2 P34913 1/20 0.38
ADRA2A P08913 1/20 0.34
ADRA1A P35348 1/20 0.34
BLM P54132 1/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
CASP1 P29466 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20913720 1.00 MEN1 (0.55) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL6560315 1.00 MEN1 (0.55) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL3385884 0.92 TSHR (0.44) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL11079513 0.86 TSHR (0.46) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL1815429 0.85 MEN1 (0.55) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL3796133 0.85 MEN1 (0.55) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL1986732 0.85 MEN1 (0.55) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL21055107 0.85 MEN1 (0.55) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL21876951 0.85 MEN1 (0.55) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL9271303 0.85 MEN1 (0.55) MEN1KMT2ATSHRMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118541342-A Method of 庄信万丰股份有限公司 2024-08-23 CN claimed
WO-2023156764-A1 PROCESS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2023-08-24 WO claimed
EP-1756353-B1 ACID DONORS FOR DYEING POLYAMIDE HUNTSMAN ADV MAT SWITZERLAND (CH) 2010-12-01 EP claimed
US-7728067-B2 Acid donors for dyeing polyamide HUNTSMAN INTERNATIONAL LLC (US) 2010-06-01 US claimed
US-20080271260-A1 Acid Donors for Dyeing Polyamide PETER HANS-JORG 2008-11-06 US claimed
US-7279304-B2 Methods for preparation of macrocyclic molecules and macrocyclic molecules prepared thereby PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-10-09 US claimed
EP-1756353-A1 ACID DONORS FOR DYEING POLYAMIDE Huntsman Advanced Materials (Switzerland) GmbH (CH) 2007-02-28 EP claimed
WO-2005106107-A1 ACID DONORS FOR DYEING POLYAMIDE HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2005-11-10 WO claimed
US-20020192773-A1 Methods for preparation of macrocyclic molecules and macrocyclic molecules prepared thereby THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2002-12-19 US claimed
US-4283581-A HYDROGENATION CATALYST OF SILICA AND COPPER OR A COPPER COMPOUND AND ZINC OXIDE CHEVRON RESEARCH COMPANY (US) 1981-08-11 US claimed
US-4149021-A Ester hydrogenation using cobalt, zinc and copper oxide catalyst CHEVRON RESEARCH COMPANY (US) 1979-04-10 US claimed
US-4087470-A CYCLIC, FROM FORMALDEHYDE AND SYNTHESIS GAS WITH HYDROGEN FLUORIDE CATALYST CHEVRON RESEARCH COMPANY (US) 1978-05-02 US claimed
CN-118541342-A Method of 庄信万丰股份有限公司 2024-08-23 CN disclosed
CN-118339216-A Silsesquioxane derivative, curable composition, hard coating agent, cured product, hard coating, and substrate 东亚合成株式会社 2024-07-12 CN disclosed
US-12016560-B2 Adjunct materials and methods of using same in surgical methods for tissue sealing CILAG GMBH INTERNATIONAL (CH) 2024-06-25 US disclosed
US-11911034-B2 Adjunct materials and methods of using same in surgical methods for tissue sealing CILAG GMBH INTERNATIONAL (CH) 2024-02-27 US disclosed
US-4149021-A Ester hydrogenation using cobalt, zinc and copper oxide catalyst CHEVRON RESEARCH COMPANY (US) 1979-04-10 US disclosed
US-4113662-A COBALT, ZINC AND COPPER CHEVRON RESEARCH COMPANY (US) 1978-09-12 US disclosed
US-4087470-A CYCLIC, FROM FORMALDEHYDE AND SYNTHESIS GAS WITH HYDROGEN FLUORIDE CATALYST CHEVRON RESEARCH COMPANY (US) 1978-05-02 US disclosed
US-4087470-A CYCLIC, FROM FORMALDEHYDE AND SYNTHESIS GAS WITH HYDROGEN FLUORIDE CATALYST CHEVRON RESEARCH COMPANY (US) 1978-05-02 US disclosed