Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | GALR3 | O60755 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20913720 | 0.92 | MEN1 (0.55) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL6560315 | 0.92 | MEN1 (0.55) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL822271 | 0.92 | MEN1 (0.55) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL243060 | 0.91 | ADRA2A (0.43) | TSHRALDH1A1TP53HIF1AADRA2A | |
| SCHEMBL5344405 | 0.88 | TSHR (0.37) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8920675 | 0.88 | TSHR (0.39) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8919715 | 0.88 | ALDH1A1 (0.58) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8726786 | 0.88 | ALDH1A1 (0.37) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL2580733 | 0.88 | ADRA2A (0.42) | TSHRALDH1A1TP53HIF1AADRA2A | |
| SCHEMBL6683309 | 0.88 | ADRA2A (0.42) | TSHRALDH1A1TP53HIF1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756353-B1 | ACID DONORS FOR DYEING POLYAMIDE | HUNTSMAN ADV MAT SWITZERLAND (CH) | 2010-12-01 | — | — | EP | claimed |
| US-7728067-B2 | Acid donors for dyeing polyamide | HUNTSMAN INTERNATIONAL LLC (US) | 2010-06-01 | — | — | US | claimed |
| US-20080271260-A1 | Acid Donors for Dyeing Polyamide | PETER HANS-JORG | 2008-11-06 | — | — | US | claimed |
| EP-1756353-A1 | ACID DONORS FOR DYEING POLYAMIDE | Huntsman Advanced Materials (Switzerland) GmbH (CH) | 2007-02-28 | — | — | EP | claimed |
| WO-2005106107-A1 | ACID DONORS FOR DYEING POLYAMIDE | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2005-11-10 | — | — | WO | claimed |
| US-9114328-B2 | Reactive distillation of a carboxylic acid and a glycol | EASTMAN CHEMICAL COMPANY (US) | 2015-08-25 | — | — | US | disclosed |
| US-9114328-B2 | Reactive distillation of a carboxylic acid and a glycol | EASTMAN CHEMICAL COMPANY (US) | 2015-08-25 | — | — | US | disclosed |
| US-9114328-B2 | Reactive distillation of a carboxylic acid and a glycol | EASTMAN CHEMICAL COMPANY (US) | 2015-08-25 | — | — | US | disclosed |
| US-20130310598-A1 | Reactive Distillation of a Carboxylic Acid and a Glycol | EASTMAN CHEMICAL COMPANY (US) | 2013-11-21 | — | — | US | disclosed |
| US-20130310598-A1 | Reactive Distillation of a Carboxylic Acid and a Glycol | EASTMAN CHEMICAL COMPANY (US) | 2013-11-21 | — | — | US | disclosed |
| WO-2013173156-A1 | REACTIVE DISTILLATION OF A CARBOXYLIC ACID AND A GLYCOL | EASTMAN CHEMICAL COMPANY (US) | 2013-11-21 | — | — | WO | disclosed |
| EP-1756353-B1 | ACID DONORS FOR DYEING POLYAMIDE | HUNTSMAN ADV MAT SWITZERLAND (CH) | 2010-12-01 | — | — | EP | disclosed |
| US-7728067-B2 | Acid donors for dyeing polyamide | HUNTSMAN INTERNATIONAL LLC (US) | 2010-06-01 | — | — | US | disclosed |
| US-20080271260-A1 | Acid Donors for Dyeing Polyamide | PETER HANS-JORG | 2008-11-06 | — | — | US | disclosed |
| EP-1756353-A1 | ACID DONORS FOR DYEING POLYAMIDE | Huntsman Advanced Materials (Switzerland) GmbH (CH) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005106107-A1 | ACID DONORS FOR DYEING POLYAMIDE | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310598-A1 | Reactive Distillation of a Carboxylic Acid and a Glycol | SORD, UGCG, DGAT1 | TSHR 3784/4885ALDH1A1 1393/4885TP53 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.