Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005012 | 0.92 | ITGB3 (0.45) | ITGB3ITGA2BF2PRSS1HDAC1 | |
| SCHEMBL8225015 | 0.89 | ACE (0.49) | ITGB3ITGA2BF2PRSS1HDAC1 | |
| SCHEMBL13766136 | 0.88 | ITGB3 (0.47) | ITGB3ITGA2BF2PRSS1HDAC1 | |
| SCHEMBL13924274 | 0.85 | HDAC1 (0.46) | ITGB3ITGA2BF2PRSS1HDAC1 | |
| SCHEMBL17497392 | 0.85 | F2 (0.41) | F2PRSS1FKBP1AACE | |
| SCHEMBL17497384 | 0.85 | F2 (0.41) | F2PRSS1FKBP1AACE | |
| SCHEMBL17497386 | 0.85 | F2 (0.41) | F2PRSS1FKBP1AACE | |
| SCHEMBL13564323 | 0.84 | ITGB3 (0.39) | ITGB3ITGA2BF2PRSS1HDAC1 | |
| SCHEMBL7931773 | 0.84 | ITGB3 (0.39) | ITGB3ITGA2BF2PRSS1HDAC1 | |
| SCHEMBL8221483 | 0.83 | PRCP (0.42) | FKBP1AACEALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057208-A2 | HCV NS3 PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 2008-05-15 | — | — | WO | disclosed |