Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 16/20 | 0.82 |
| ▸ | PLD2 | O14939 | 13/20 | 0.82 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11972667 | 1.00 | PLD1 (0.82) | PLD1PLD2SLC6A9 | |
| SCHEMBL12965084 | 0.90 | PLD1 (1.00) | PLD1PLD2SLC6A9 | |
| SCHEMBL15786689 | 0.90 | PLD1 (1.00) | PLD1PLD2SLC6A9 | |
| SCHEMBL12964986 | 0.90 | PLD1 (1.00) | PLD1PLD2SLC6A9 | |
| SCHEMBL11991979 | 0.90 | PLD1 (0.91) | PLD1PLD2 | |
| SCHEMBL11991983 | 0.90 | PLD1 (0.91) | PLD1PLD2 | |
| Trifluoroacetic Acid SCHEMBL11973828 | 0.87 | PLD1 (0.90) | PLD1PLD2 | |
| Trifluoroacetic Acid SCHEMBL11972550 | 0.87 | PLD1 (0.90) | PLD1PLD2 | |
| Trifluoroacetic Acid SCHEMBL11972548 | 0.87 | PLD1 (0.90) | PLD1PLD2 | |
| SCHEMBL11992042 | 0.87 | PLD1 (0.74) | PLD1PLD2SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456307-B1 | ISOFORM SELECTIVE PHOSPHOLIPASE D INHIBITORS | UNIV VANDERBILT (US) | 2016-11-02 | — | — | EP | disclosed |
| US-9127005-B2 | Isoform selective phospholipase D inhibitors | VANDERBILT UNIVERSITY (US) | 2015-09-08 | — | — | US | disclosed |
| US-20120214832-A1 | ISOFORM SELECTIVE PHOSPHOLIPASE D INHIBITORS | VANDERBILT UNIVERSITY | 2012-08-23 | — | — | US | disclosed |
| EP-2456307-A1 | ISOFORM SELECTIVE PHOSPHOLIPASE D INHIBITORS | Vanderbilt University (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011011680-A1 | ISOFORM SELECTIVE PHOSPHOLIPASE D INHIBITORS | VANDERBILT UNIVERSITY (US) | 2011-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214832-A1 | ISOFORM SELECTIVE PHOSPHOLIPASE D INHIBITORS | PLD1, PLD2, PLA2G2D | PLD1 1/4885PLD2 2/4885SLC6A9 3344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.