Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 4/20 | 0.40 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8223251 | 1.00 | POLB (0.44) | POLBKMT2ATDP1LTA4HL3MBTL1 | |
| SCHEMBL7908800 | 0.83 | TNF (0.41) | POLBKMT2ATDP1NOS2NOS1 | |
| SCHEMBL7225511 | 0.83 | TNF (0.41) | POLBKMT2ATDP1NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL8205619 | 0.82 | NOS2 (0.42) | POLBKMT2ATDP1NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL8205615 | 0.82 | NOS2 (0.42) | POLBKMT2ATDP1NOS2NOS1 | |
| SCHEMBL7911885 | 0.79 | NOS2 (0.49) | KMT2ANOS2NOS1NOS3CYP1A2 | |
| SCHEMBL7226879 | 0.79 | NOS2 (0.49) | KMT2ANOS2NOS1NOS3CYP1A2 | |
| SCHEMBL7909528 | 0.78 | NOS2 (0.48) | KMT2ANOS2NOS1NOS3CYP1A2 | |
| SCHEMBL7224528 | 0.78 | NOS2 (0.48) | KMT2ANOS2NOS1NOS3CYP1A2 | |
| SCHEMBL9121869 | 0.78 | SLC1A3 (0.48) | DPP8DPP7SIRT1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885188-B1 | HYDROXYAMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2000-09-27 | — | — | EP | claimed |