SCHEMBL822376

SCHEMBL822376

Cc1ccc(Sc2cccc(C)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.48
BCL2 P10415 1/20 0.44
MCL1 Q07820 1/20 0.44
SLC5A2 P31639 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
MAPT P10636 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HKDC1 Q2TB90 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
HTR1A P08908 2/20 0.41
HTR3A P46098 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
IDO1 P14902 1/20 0.41
HTR2C P28335 1/20 0.41
HTR6 P50406 1/20 0.41
MLYCD O95822 1/20 0.41
GRM5 P41594 1/20 0.41
MGLL Q99685 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31038384 1.00 ACHE (0.48) ACHEBCL2MCL1SLC5A2L3MBTL1
SCHEMBL10710202 0.95 ACHE (0.52) ACHEL3MBTL1MAPTNPSR1HTR1A
SCHEMBL11125164 0.91 ACHE (0.48) ACHEBCL2MCL1L3MBTL1MAPT
SCHEMBL31351862 0.91 MCL1 (0.47) ACHEBCL2MCL1SLC5A2L3MBTL1
SCHEMBL575896 0.91 ACHE (0.58) ACHEL3MBTL1MAPTNPSR1MEN1
SCHEMBL29543680 0.91 ACHE (0.58) ACHEL3MBTL1MAPTNPSR1MEN1
SCHEMBL29468631 0.91 ACHE (0.58) ACHEL3MBTL1MAPTNPSR1MEN1
SCHEMBL3894284 0.88 ACHE (0.50) ACHEL3MBTL1MAPTNPSR1MEN1
SCHEMBL8373547 0.85 NR1H2 (0.56) ACHEBCL2MCL1SLC5A2MAPT
SCHEMBL2421296 0.85 CYP3A4 (0.56) ACHEMAPTMEN1KMT2AHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024605-B2 Polyamide-based composite film and display device comprising same SK MICROWORKS SOLUTIONS CO., LTD. (KR) 2024-07-02 US disclosed
US-11873372-B2 Polyamide-imide film, preparation method thereof, and cover window comprising same SK MICROWORKS CO., LTD. (KR) 2024-01-16 US disclosed
US-11840611-B2 Polyamide-based composite film and display device comprising same SK MICROWORKS SOLUTIONS CO., LTD. (KR) 2023-12-12 US disclosed
US-11820893-B2 Polymer film and preparation method thereof SK MICROWORKS CO., LTD. (KR) 2023-11-21 US disclosed
US-11820874-B2 Polyamide-based film, preparation method thereof, and cover window comprising same SK MICROWORKS CO., LTD. (KR) 2023-11-21 US disclosed
US-11820893-B2 Polymer film and preparation method thereof SK MICROWORKS CO., LTD. (KR) 2023-11-21 US disclosed
US-11814483-B2 Separation membrane comprising coating layer, method of preparing same, and battery using same SAMSUNG SDI CO., LTD. (KR) 2023-11-14 US disclosed
US-11814483-B2 Separation membrane comprising coating layer, method of preparing same, and battery using same SAMSUNG SDI CO., LTD. (KR) 2023-11-14 US disclosed
US-20230357505-A1 POLY(AMIDE-IMIDE) COPOLYMER, METHOD OF MANUFACTURING THE SAME, POLY(AMIDE-IMIDE) COPOLYMER FILM, WINDOW FOR DISPLAY DEVICE, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-09 US disclosed
US-11805616-B2 Polyimide-based composite film and display device comprising same SK MICROWORKS CO., LTD. (KR) 2023-10-31 US disclosed
WO-2009113747-A1 PREPARATION METHOD OF POLYBENZOXAZOLES BY THERMAL REARRANGEMENT, POLYBENZOXAZOLES PREPARED THEREBY, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-09-17 WO disclosed
WO-2009107889-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-09-03 WO disclosed
US-7360883-B2 Active ray curable ink, image forming method and ink-jet recording apparatus KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-04-22 US disclosed
US-20070244120-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BAYER HEALTHCARE LLC 2007-10-18 US disclosed
US-20070244120-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BAYER HEALTHCARE LLC 2007-10-18 US disclosed
WO-2007064869-A2 CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES YALE UNIVERSITY (US) 2007-06-07 WO disclosed
WO-2007064869-A2 CATALYSTS FOR ARYL SULFIDE SYNTHESIS AND METHOD OF PRODUCING ARYL SULFIDES YALE UNIVERSITY (US) 2007-06-07 WO disclosed
US-4026859-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US disclosed
US-4026860-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US disclosed
US-4026861-A AROMATIZATION CATALYST HERCULES INCORPORATED (US) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244120-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BRAF, RAF1, ARAF ACHE 4822/4885BCL2 1503/4885MCL1 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.