Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185765 | 0.87 | GAA (0.40) | GAANFKB1NFKB2RELAKDM1A | |
| SCHEMBL8181064 | 0.85 | GAA (0.39) | GAANFKB1NFKB2RELAKDM1A | |
| SCHEMBL8187705 | 0.85 | GAA (0.39) | GAANFKB1NFKB2RELAKDM1A | |
| SCHEMBL8181233 | 0.84 | ADAMTS4 (0.39) | GAANFKB1NFKB2RELAKDM1A | |
| SCHEMBL10163713 | 0.84 | GAA (0.38) | GAANFKB1NFKB2RELAKDM1A | |
| SCHEMBL8183929 | 0.84 | GAA (0.38) | GAANFKB1NFKB2RELAKDM1A | |
| SCHEMBL8247296 | 0.83 | GAA (0.37) | GAANFKB1NFKB2RELAKDM1A | |
| SCHEMBL4082429 | 0.83 | S1PR1 (0.40) | GAANFKB1NFKB2RELAKDM1A | |
| SCHEMBL5429659 | 0.83 | S1PR1 (0.40) | GAANFKB1NFKB2RELAKDM1A | |
| SCHEMBL8179948 | 0.83 | GAA (0.37) | GAANFKB1NFKB2RELAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002671-A2 | METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-01-03 | — | — | WO | disclosed |