Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.42 |
| ▸ | IDH1 | O75874 | 5/20 | 0.36 |
| ▸ | IDH2 | P48735 | 4/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.32 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30798663 | 0.82 | LOXL2 (0.44) | MALT1IDH1IDH2LOXL2LOX | |
| Hydrochloric Acid SCHEMBL20815622 | 0.82 | MALT1 (0.41) | MALT1IDH1IDH2LOXL2LOX | |
| Hydrochloric Acid SCHEMBL30813051 | 0.82 | MALT1 (0.41) | MALT1IDH1IDH2LOXL2LOX | |
| SCHEMBL19583716 | 0.80 | MALT1 (0.42) | MALT1IDH1IDH2LOXL2GRM2 | |
| SCHEMBL8171795 | 0.80 | IDH1 (0.42) | MALT1IDH1IDH2GRM2AAK1 | |
| SCHEMBL3662853 | 0.80 | MALT1 (0.42) | MALT1IDH1IDH2GRM2 | |
| SCHEMBL13162796 | 0.80 | LOXL2 (0.43) | MALT1IDH1IDH2LOXL2LOX | |
| SCHEMBL8225228 | 0.77 | IDH1 (0.40) | MALT1IDH1IDH2 | |
| SCHEMBL17109739 | 0.77 | MALT1 (0.40) | MALT1IDH1IDH2GRM2AAK1 | |
| SCHEMBL24108548 | 0.76 | MALT1 (0.39) | MALT1IDH1IDH2GRM2TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002671-A2 | METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-01-03 | — | — | WO | disclosed |