Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 13/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218861 | 0.85 | CACNA1H (0.70) | CACNA1HOPRK1 | |
| SCHEMBL8218790 | 0.85 | CACNA1H (0.73) | CACNA1HS1PR2 | |
| SCHEMBL8225665 | 0.80 | CACNA1H (0.45) | CACNA1H | |
| SCHEMBL8226405 | 0.79 | CACNA1H (0.50) | CACNA1HALDH1A1OPRK1 | |
| SCHEMBL8224706 | 0.78 | CACNA1H (0.49) | CACNA1HALDH1A1 | |
| SCHEMBL8224611 | 0.78 | CACNA1H (0.49) | CACNA1HALDH1A1OPRK1 | |
| SCHEMBL8229746 | 0.78 | CACNA1H (0.61) | CACNA1H | |
| SCHEMBL8224560 | 0.75 | CACNA1H (0.88) | CACNA1HS1PR2 | |
| SCHEMBL8224484 | 0.75 | CACNA1H (0.57) | CACNA1H | |
| SCHEMBL8218795 | 0.75 | CACNA1H (0.75) | CACNA1HOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033456-A1 | SPIRO-CONDENSED AZETIDINE DERIVATIVES USEFUL IN TREATING PAIN, DIABETES AND DISORDERS OF LIPID METABILISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |