Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB2 | Q9UBS0 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.42 |
| ▸ | CASP1 | P29466 | 7/20 | 0.42 |
| ▸ | CASP7 | P55210 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | USP2 | O75604 | 6/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15958616 | 0.81 | RPS6KB2 (0.47) | RPS6KB2ALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL8226859 | 0.78 | RPS6KB2 (0.50) | RPS6KB2ALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL7907933 | 0.78 | ALDH1A1 (0.39) | RPS6KB2ALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL8380330 | 0.78 | CYP1A2 (0.41) | RPS6KB2ALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL7907910 | 0.75 | CYP1A2 (0.41) | RPS6KB2ALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL8380552 | 0.75 | CYP1A2 (0.44) | RPS6KB2ALDH1A1CYP1A2CASP1CASP7 | |
| SCHEMBL31265460 | 0.75 | RPS6KB2 (0.61) | RPS6KB2ALDH1A1CASP1CASP7MEN1 | |
| SCHEMBL578071 | 0.75 | RPS6KB2 (0.61) | RPS6KB2ALDH1A1CASP1CASP7MEN1 | |
| SCHEMBL8230198 | 0.71 | RPS6KB2 (0.51) | RPS6KB2ALDH1A1CASP1CASP7MEN1 | |
| SCHEMBL20673873 | 0.70 | KDM4E (0.33) | CYP2C9KDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002924-A2 | QUINOXALINYL MACROCYCLIC HEPATITIS C VIRUS SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-01-03 | — | — | WO | disclosed |